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5h
Google DeepMind Releases AlphaGenome Atlas
The human genome is made of about 3 billion base pairs of DNA — but much of it remains a mystery. Scientists understand the 2% of the human genome that codes for proteins relatively well, but have only limited knowledge of the remaining 98%. Our AlphaGenome model has already shown how single changes in these non-coding DNA regions can disrupt molecular processes like protein production, but the bigger picture remained unclear.
Today, we're introducing AlphaGenome Atlas, a database that predicts…
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6h
DaVinci Resolve 21.1
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2h
On the Navier–Stokes Millennium Prize Problem
We’re sharing a solution to the Navier–Stokes existence and smoothness problem, one of the Millennium Prize Problems. This proof, produced by an internal OpenAI system, shows that the dynamics of the Navier-Stokes equations for fluid motion can develop a singularity in finite time. We’re sharing both a writeup of the proof and a formalization in Lean.
The Millennium Prize Problems(opens in a new window) represent some of the deepest questions at the frontier of mathematics. The question of whe…
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5h
Benchmarking Qwen3.8 27B quantizations: 4-bit holds up, 1-bit collapses
How much GPU RAM do you actually need to run Qwen3.8 27B without sacrificing quality?
The full BF16 model weighs 55 GB, putting it beyond most consumer hardware. Yet the 17 GB Q4_K_M matches the full model on a popular agentic coding benchmark, Terminal-Bench 2.1. It fits on a 24 GB card such as RTX 4090, still leaving room for about 64k tokens of context.
Compression eventually hits a cliff. At 1 bit, the model performs around random chance on GPQA Diamond, and longer reasoning makes it worse…
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2h
OUI-1: world's first model for Generative UI
A DiffusionGemma finetune at 71.7% on the Generative UI Benchmark, 5.5x its base.
OUI-1 is a finetuned DiffusionGemma model that writes user interfaces in openui-lang. It is 26BA4B model that can run on consumer grade GPU (RTX 5090, at FP8), and the weights are on Hugging Face under the Gemma Terms of Use.
Agent-driven interfaces are the future of software. But getting there comes down to three constraints. Interfaces must be generated in under a second. They must be reliable enough to use as…
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1d
The Helicopter with Radioactive Blades
Sometimes you find gold in unexpected places. In this case, it’s from a video about the CH-53 helicopter. The CH-53 Sea Stallion first entered service in 1966. It’s a huge helicopter, capable of lifting immense amounts of weight. All that weight hangs from 6 (or 7 on some models) rotor blades. The problem was detecting problems with the blades before they grew into a catastrophic failure.
Much like a fixed-wing aircraft wing, the CH-53 rotor blades are designed with a spar as the main structura…
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3h
Show HN: LLM Attention Visualization
One interesting thing about transformer-based large language models are that, during the generation phase, it is able to draw information from any of its previous tokens. But it needs to be selective; if every token affects the generation equally, it won't be very effective. This process needs a mechanism to decide how much a token affects the next token.
Turns out, we can visualize this mechanism!
You can tap or hover over any of the generated tokens to see the past tokens that affected* the…
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3h
Connecting the Machines
The next step for Herdr is connecting the machines.
Herdr already has more than 700,000 downloads and close to 1,000 plugins. There is a big community behind it, with people using it to manage their agents and their local machines.
Herdr already has --remote, so you can attach to a remote machine. As agents run for multiple hours, sometimes you want them on a machine that stays alive 24/7. You don’t want to keep your laptop open just because an agent is still working.
I think we’re also start…
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3h
LG TVs caught spying even when offline or on standby
is a news editor with over a decade’s experience in journalism. He previously worked at Android Police and Tech Advisor.
LG smart TVs are almost constantly logging and uploading data about owners and their homes, even when offline or on standby mode, according to a new report from YouTube channel Gamers Nexus. The company’s TV sets scan Wi-Fi networks for nearby devices, record audio logs through their microphones, and use audio and video sampling to recognize exactly what you’re watching from…
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5h
I-have-ADHD: A skill to stop coding agents from burying the answer
ADHD-friendly outputs. No ADHD diagnosis needed!
🇬🇧 · 🇨🇳 · 🇧🇷 · 🇯🇵 · 🇻🇳 · 🇰🇷 · 🇹🇭
Install the i-have-adhd skill/plugin from https://github.com/ayghri/i-have-adhd, refer to the repo's AGENTS.md for instructions.
Or 🔗 check the installation instructions.
What it does
A skill for your coding assistant that stops it from burying the answer. Action first. Steps numbered. No "Hope this helps!"
What changes
Before
Great question! Let me think about this. Your auth flow has a few moving pieces:…
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3h
Intratumoral T cell activation kills tumors regardless of T cell specificity | Nature Immunology
The CITE-seq data have been deposited in the Gene Expression Omnibus under the accession no. GSE324375. All other data are present in the article and Supplementary Information.
Wang, S. Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8+ T cells. Proc. Natl Acad. Sci. USA 113, E7240–E7249 (2016).
Article CAS PubMed PubMed Central Google Scholar
Corrales, L. et al. Direct activation of STING in the tumor microenvironment leads t…
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3h
Report flags thousands of food packaging chemicals for replacement. Among the 15,159 chemicals, the team identified 38 structural groups with a high proportion of harmful chemicals, including per- and polyfluoroalkyl substances (PFAS), phthalates, and organophosphates.
A new study identifies the chemical groups that packaging manufacturers and regulators should target for replacement in the food system to protect human health.
More than 4,000 chemicals used in food packaging are structurally similar to chemicals known to be hazardous to human health, according to the study by researchers with the Food Packaging Forum (FPF). And 70% of those have insufficient hazard data, the researchers found.
The study was published Tuesday in the journal Environmental Scie…
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4h
Scientists have created concrete using treated human waste, and the resulting material was up to 42% stronger than conventional concrete. Researchers say the approach could reduce waste while lowering the environmental impact of construction.
Could the concrete of the future contain a little bit of poop? (Lighthouse Films/Getty Images)
Concrete is, quite literally, the foundation of the modern world.
Almost every construction project in the world uses the material in some form. There's just one problem, and that's a big one: Making one of its central ingredients – cement – is horrendously bad for the environment.
The act of heating and processing limestone to make cement is one of the world's foremost sources of carbon dioxide emi…
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4h
New molecular magnet design boosts magnetic memory performance
By combining the most successful features of previous molecular magnet designs, researchers have created high-performing lanthanide-based molecules that could support future ultra-high-density data storage technologies.
Structure of a dysprosium cyclopentadienyl-amide compound determined by single crystal X-ray diffraction. Counterion and hydrogen atoms not shown. Key - Dysprosium Cyan, Nitrogen Blue, Silicon Orange, Carbon Grey.
Researchers at The University of Manchester and the Australian N…
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5h
Periodical cicadas suffer legacy effects of deforestation and cannot be reintroduced to areas of local extirpation.
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1h
White House Officially Removes Racist 'Tetris' Clone After Legal Threat
It looks like if they wanted to, video game companies could get the Trump admin to stop ripping them off.
Image: Monstars, Resonair/Enhance Games
Sign in to your Polygon.com account
It looks like video game companies actually can get the Trump administration to budge. Shortly after the White House posted a new “Arcade” section on its official website featuring xenophobic web browser games, the administration just removed a Tetris clone from its selection of slop.
On Sept. 4, the White House l…
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1h
Bernie Sanders Says ’We Can’t Allow’ AI Billionaires To ’Play God’: Bill Threatens ’Corporate Death Penalty’ | Sanders and Casar propose legislation to halt AI superintelligence development, starting debate over tech regulation
Sen. Bernie Sanders has stepped up his campaign for tougher artificial intelligence rules, arguing that decisions about increasingly powerful AI should not be left to a small group of technology executives and investors.
The Vermont independent made the case for greater public oversight as he and Rep. Greg Casar announced plans for forthcoming legislation that would permanently prohibit the development and deployment of artificial superintelligence.
The proposal would also temporarily pause ad…
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2h
OpenAI Says It Has Solved a Millennium Prize Problem—a Holy Grail of Math
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2h
Paramount Caught Using ‘Astroturf’ Group To Drum Up Fake Support For Merger
We’ve well established how the $111 billion Paramount and Warner Brothers merger is terrible for labor, creatives, consumers, and markets. But the kind of behaviors Paramount leadership have been engaged in to sell the deal also give a pretty clear indication what kind of company we’re dealing with, and why they shouldn’t be allowed to control an even bigger slice of U.S. media.
Recent desperate moves by the company include accusing all deal critics of being “antisemitic,” threatening to take P…
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1h
Trump told Putin he wants swift end to Ukraine war and US-Russia ties restored, Kremlin says
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2h
'Mexico Is Nobody's Colony': Sheinbaum Strikes Back Against Border Military Map Controversy
Mexican President Claudia Sheinbaum Pardo is pictured alongside a map published by U.S. President Donald Trump on Truth Social. Eloisa Sanchez/Getty Images; Donald Trump/Truth Social; composite by Miguel Paiva/Latin Times
Mexican President Claudia Sheinbaum needed one sentence to turn an unlabeled internet graphic into a full-blown diplomatic incident. Hours after Donald Trump posted an AI-generated map draping the U.S. flag across Mexico, Canada, Greenland and roughly thirty other countries an…
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3h
Iceland calls post ‘wholly inappropriate,’ summons U.S. ambassador
Updated: September 08, 2026 at 9:48a.m. EDT
Published: September 08, 2026 at 9:40a.m. EDT
CTV News U.S. Political Analyst Eric Ham on what Trump’s latest social media rant signifies and what it will take for both sides to get back to the table.
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3h
Iran Guards claim capture of ‘one of smartest’ US submarines in Strait of Hormuz | World News
...
The IRGC said it would release photographs and detailed video footage of the captured US asset later.
Iran on Tuesday captured an unmanned US submarine in the strategic Strait of Hormuz, which Tehran has blockaded during the months-long war in West Asia, Iran's Revolutionary Guards (IRGC) claimed.
Vessels transit the Hormuz Strait off the coast of Iran's southern port city of Bandar Abbas. (AFP/Representational Image)
"The IRGC naval forces captured one of the most modern, unmanned, and s…
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3h
EU and Canada Plan Far-Reaching Alliance to Strengthen Partnership
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15h
I changed my license to EUPL
In the last 28 years of publishing software, I’ve had three distinct eras of software licensing. All of my recent stuff is available under the European Union Public License 1.2, and I thought to explain why.
Midgard was all LGPLv2. This was a simpler time, and there weren’t that many free software licenses around. Since Midgard was a web framework, using a weak copyleft license felt like the right thing to do. The example website shipping with Midgard was X11 licensed.
When I started working m…
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12h
The state of European cloud providers in 2026
Recently I went on the hunt for a new server provider for my personal use. I have been getting on quite well with an old laptop shoved into my utility closet and Tailscale for some years now, but now there are some things I would like to be accessible outside my VPN.
With the situation outside looking like it does, I figured it would be prudent to look for an European cloud provider. Plus, it is always nice to support the home team. The EU has been very loudly proclaiming the need for a “sovere…
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6h
Switching Password Managers in 2026
Important Note: Although I work at Apple in the password management and app/website authentication spaces, in this post I am speaking only for myself, personally. There is no “news” in this post or any kind of “inside scoop”. Please do share this post, but if I see “Apple’s Ricky Mondello” anywhere, I’ll be sad. My intention is to help people benefit from data portability and interoperability work I’ve personally participated in. Nobody should feel locked into their password manager. :)
Would y…
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9h
Extreme Server Side Rendering
What is (Normal) Server Side Rendering?
Before we get into extreme server side rendering (XSSR), we have to talk about normal server side rendering (SSR). This comes in two flavours, which I'm calling old-school and new-school.
Old-school SSR involves having a server which uses some logic to create the HTML of the web page on-the-fly. For example, you might hit /users/39, and it might give you the details of user 39. These details might be from a database, or they might come from somewhere els…
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16h
Jellyfin 12.0
We are pleased to bring you Jellyfin 12.0, our new stable release. This release continues in the same direction as 10.11: finishing what the database conversion started, turning that new foundation into real performance work, and finally giving books and comics the support they have deserved for years.
If you just want a quick summary of what you need to know to get your system upgraded and running, please read on to the "TL; DR" section just below, or keep reading for a full explanation of all…
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13h
Bitap: my favorite string matching algorithm
A classic problem is to find the first occurrence of a pattern $P$ in a string $T$. There are various classic (and very elegant!) algorithms to solve this problem efficiently, such as Boyer-Moore, Knuth-Morris-Pratt, and two-way. In this post I want to provide an exposition of a less well-known algorithm, the bitap or shift-and algorithm1, that runs efficiently when the pattern $P$ is relatively short (of length less than the width of a machine word.) Despite its constraints, I like it a lot bec…
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10h
How to get a free .arpa domain
This post is also available over on get-arpa-domain.0.4.1.0.9.0.f.1.0.7.4.0.1.0.0.2.ip6.arpa (opens in a new tab)!
On the internet, .arpa is the top level domain reserved for critical internet infrastructure. It isn’t open to public registration, so you can’t own mysite.arpa sadly. However, this isn’t the only way to reserve some real-estate on .arpa - there are many different services that you can abuse to get your own DNS records, and hence your own website.
I first learned about this throug…
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1d
Einstein's Equivalence Principle Passes a Quantum Test
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1d
Scientists Captured Trillionth-of-a-Second Snapshots of a Chemical Reaction Essential to Life
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1d
More Than 1,200 Genetic Variants Linked to Personality Traits Like Extraversion and Conscientiousness
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1d
165-Million-Year-Old Insect Fossils Help Reconstruct What a Jurassic Forest May Have Sounded Like
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3d
Ancient Blacksmiths May Have Hammered Away a Meteorite's Cosmic Signature
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3d
Young Chimpanzees Develop Distinct Vocal Accents That Become Stronger With Age
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3d
Hawaiʻi Students Help Name a Pair of Merging Galaxies More Than 200 Million Light-Years Away
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1h
Campaigns operated by JTRIG have broadly fallen into two categories: cyber attacks and propaganda efforts. The propaganda efforts (named "Online Covert Action") utilize "mass messaging" and the "pushing [of] stories" via the medium of Twitter, Flickr, Facebook and YouTube.
The Joint Threat Research Intelligence Group (JTRIG) is a unit of the Government Communications Headquarters (GCHQ), the British intelligence agency.[1] The existence of JTRIG was revealed as part of the global surveillance disclosures in documents leaked by the former National Security Agency contractor Edward Snowden.[2]
The scope of the JTRIG's mission includes using "dirty tricks" to "destroy, deny, degrade [and] disrupt" enemies by "discrediting" them, planting misinformation and shutting…
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3h
In her definition of transmisogyny, Serano does not limit those affected by transmisogyny to individ…
From Wikipedia, the free encyclopedia
Graffiti in Berlin branding the Liebig 34 squatters as transmisogynists
Transmisogyny, otherwise known as trans-misogyny and transphobic misogyny, is the intersection of transphobia and misogyny as experienced by trans women and transfeminine people.[1][2] The term was coined by Julia Serano in her 2007 book Whipping Girl to describe a particular form of oppression experienced by trans women.[3][4][5] In a 2017 interview with The New York Times, Serano expl…
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5h
Contrary to popular belief, there is little archaeological evidence of 17th-century sailors eating dodo birds, and the introduction of invasive species (including dogs, cats, rats, pigs, and monkeys) is the main cause attributed to their extinction
Temporal range:
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6h
Why is BSW considered far left while Die Linke is left wing on Wikipedia?
Die Linke and BSW are two left wing parties in Germany. However, Die Linke is more socially liberal while BSW is more socially conservative. Why does Wikipedia label Die Linke's political position to be left wing while BSW is considered left wing to far left?
https://en.wikipedia.org/wiki/Die_Linke
https://en.wikipedia.org/wiki/Sahra_Wagenknecht_Alliance
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6h
In the aftermath of the August 2020 police shooting of Jacob Blake, protests, riots, and civil unrest occurred in Kenosha, Wisconsin. The demonstrations were marked by daily peaceful protesting followed by confrontations with law enforcement, rioting, and arson at night.
Kenosha unrest
Part of the United States racial unrest
and reactions to the shooting of Jacob Blake
Justice for Jacob Blake Poster
Date August 23 – September 1, 2020
(1 week and 2 days)
Location
Kenosha, Wisconsin
Caused by Shooting of Jacob Blake
Methods
Protests
demonstrations
civil disobedience
civil resistance
rioting
arson
Status State of emergency August 25 – September 2, 2020; and January 4–11, 2021[1]
Parties
Black Lives Matter
Federal government of the United States
Wisconsin
Ken…
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7h
This Week in Canada: America Is Our Enemy and Doesn’t Even Know It
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10h
Spencer Cox: The Day Charlie Kirk Died. Plus. . .
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11h
Ten-Minute Warning: The Hypersonic Threat
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20h
She Let Her Son Go for a Walk. Now She’s a Convicted Criminal.
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20h
Trump Is Charting a New Course on Iran
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21h
Spencer Cox: Inside the Search for Charlie Kirk’s Killer
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1d
Arthur Brooks: How to Be Happy at College
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10h
ST
Write Things Down
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4d
ST
2026.36: Friction and Feedback
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4d
ST
An Interview with OpenAI President Greg Brockman About Astra and Alignment
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6d
ST
Fable 5.1, Enterprise Frontier Safeguards
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2d
MA
Have the frontier labs mixed up AI safety and security?
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4d
AN
Cancer Capital: VC didn’t use to work like this
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6d
AN
VC isn’t VC anymore — understanding the rise of Cancer Capital
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3h
DW
Pretraining progress is mostly coming from data
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7h
NO
Everyone is Reading Lonesome Dove
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4d
NO
Weekly Dose of Optimism #209
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